Brown University’s Sc.B. in Computational Biology is a highly interdisciplinary program integrating biology, computer science, applied mathematics, and statistics to analyze and model biological phenomena through computational means. Housed within The College at Brown University, the program equips students with tools to advance research in genomics, medicine, neuroscience, ecology, and biotechnology.
Students select from three tracks Computer Science, Biological Sciences, or Applied Mathematics & Statistics, allowing them to specialize based on their career goals and academic interests. The program emphasizes real-world applications through a senior capstone or research experience, preparing graduates for roles in biomedical research, pharma, healthcare data science, or graduate study in bioinformatics and related disciplines.
Course Overview
Prerequisites (0–3 courses):
Single-variable calculus (Part II or equivalent)
Multivariable calculus
Introductory biology (The Foundation of Living Systems or equivalent)
Core Curriculum:
Biology: Genetics, Biochemistry or Cell & Molecular Biology
Chemistry: Organic Chemistry I or Equilibrium, Rate, and Structure
Computer Science:
Introductory programming sequence
Discrete Structures and Probability
Mathematics & Statistics: APMA 1655 – Intro to Probability and Statistics with Calculus
Computational Biology Core:
Inference in Genomics and Molecular Biology
Computational Molecular Biology
Track Options (Choose One):
Computer Science Track
Three advanced CS electives (e.g., AI, ML, Databases, Vision)
Three advanced quantitative/computational electives (e.g., Algorithms, Biostatistics, R for Data Analysis)
Biological Sciences Track
Four advanced biology courses forming a theme (e.g., Neurobiology, Genomics)
Two advanced computational/quantitative electives
Applied Mathematics & Statistics Track
Three advanced applied math/statistics courses (e.g., ODEs, PDEs, Biostatistics)
Three advanced computational biology or ML-related courses
Capstone Requirement:
Senior research project supervised by a faculty member
OR a 2000-level computational biology course with a research component
Honors:
Majority of As or “S with distinction” in concentration courses
At least one (preferably two) semesters of research with faculty
Completion and public defense of an honors thesis
Senior Capstone: Required research project or advanced course with research focus
Optional Honors Thesis: In-depth research under faculty guidance
Interdisciplinary curriculum combining hands-on lab work, statistics, and computer science
Access to faculty in biology, computer science, and applied math departments for guidance
Excellent preparation for graduate study in bioinformatics, computational biology, or medicine
Competitive entry into biotech and pharmaceutical companies as analysts or scientists
Trains students for roles at the intersection of life sciences and technology
High success rate in pursuing PhDs, MDs, or research-intensive careers
Supported by Brown’s open curriculum, advising system, and research opportunities
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