The B.S. in Biophysics at Wake Forest University brings physics, biology, chemistry, biochemistry and mathematics together to help students understand living systems quantitatively, from molecules and cells to tissues and disease. It is well suited to students interested in research, biotechnology, medicine, computational science and other STEM fields, with opportunities to explore biological systems through physical, mathematical and computational approaches.
Curriculum Structure
Year 1: Students establish their foundation in quantitative and experimental science through PHY 123/124 General Physics, MTH 111/112 Calculus, and CHM 111/111L College Chemistry. These courses build the physics, mathematics and chemistry knowledge needed for more advanced study of biological systems.
Year 2: Students develop a deeper understanding of physical, mathematical, chemical and biological principles through PHY 215 Elementary Modern Physics, MTH 205 Linear Algebra and Differential Equations, CHM 122/122L Intro Organic Chemistry & Lab, and BIO 150/150L Biology I and Biology I Lab. They also take PHY 262 Mechanics and PHY 265/266 Intermediate Laboratory, strengthening their analytical and experimental skills.
Year 3: The program becomes increasingly specialized, with students choosing advanced areas such as PHY/BIO 307/325 Biophysics and Biophysical Methods & Laboratory, PHY 320 Physics of Biological Macromolecules, PHY/CSC 385 Bioinformatics, or CSC 387 Computational Systems Biology. Students also complete BIO 160/160L Biology II and Biology II Lab, CHM 280 College Chemistry II, and begin research through PHY 381 Research or approved research alternatives.
Year 4: Students continue advanced biophysics study through an additional elective while completing PHY 230 Electronics and BIO/BMB/CHM 370 Biochemistry: Macromolecules and Metabolism. Research continues through PHY 381 or approved chemistry/biology research courses, allowing students to connect classroom knowledge with faculty-led scientific investigation.
Focus areas: Biophysics, biological macromolecules, molecular biology, computational systems biology, bioinformatics, biomechanics, microscopy, blood flow, biomolecular dynamics, drug discovery, biochemistry and quantitative biology.
Learning outcomes: Apply physics, chemistry, mathematics and computational methods to biological systems; analyze molecular and cellular processes quantitatively; develop laboratory and research skills; use computational approaches to investigate biological questions; and communicate scientific findings through interdisciplinary research.
Professional alignment (accreditation): Wake Forest University is accredited by the Southern Association of Colleges and Schools Commission on Colleges (SACSCOC) to award baccalaureate, master's and doctoral degrees. The university does not identify a separate specialized professional accreditation for the B.S. in Biophysics.
Reputation (employability rankings): Wake Forest reports that 97% of graduates in recent years were employed or enrolled in graduate programs within six months of graduation. In its 2026 LinkedIn Top Colleges announcement, Wake Forest reported a No. 17 overall ranking and No. 10 for job placement; these are university-wide measures rather than rankings specifically for the Biophysics B.S.
Wake Forest's Biophysics B.S. gives students substantial opportunities to learn through research alongside faculty rather than relying only on classroom study. The Physics Department encourages undergraduates to join research groups through PHY 381, URECA summer programs or paid research positions, with work spanning experimental, computational and theoretical biophysics.
Students can work in research environments investigating blood and clot mechanics, biomolecular dynamics, microscopy, molecular machines and drug discovery. Facilities include advanced optical and atomic-force microscopy equipment, while faculty research also uses computational approaches, molecular modeling and next-generation sequencing.
Key practical and research opportunities include:
PHY 381 Research Internship — required for at least 1.5 hours and provides a structured route into faculty-led research.
Biophysical Methods Laboratory (PHY 325) — develops practical experience with methods used in biophysics.
Atomic Force Microscopy (AFM) — used in faculty research to study biological samples, fibrin fibers, blood clots and biological molecules.
Fluorescence microscopy — used for biological imaging and research into molecular and cellular systems.
Optical tweezers and advanced microscopy — available through the department's optical microscopy facilities.
Computational biophysics — research includes protein and RNA folding, biomolecular assembly, molecular machines and GPU-based programming.
Bioinformatics and computational systems biology — students can select PHY/CSC 385 Bioinformatics or CSC 387 Computational Systems Biology.
Experimental research — undergraduate projects can include studying blood and clot mechanics, building and testing electronic devices, and imaging cells and molecules.
URECA summer research — students can participate in summer research projects with faculty mentors.
Olin Physical Laboratory research facilities — biophysics faculty conduct experimental and computational research in dedicated laboratory spaces.
The Biophysics B.S. provides a foundation for careers and further study across biotechnology, research, medicine, data science and other quantitative STEM fields. Wake Forest's Physics Department reports that its graduates enter industry, government, research and development, and graduate or professional programs, while the Biophysics program specifically highlights careers such as clinical research, laboratory science, microbiology and pharmacology.
Typical job roles: Biophysics Researcher, Clinical Research Coordinator, Laboratory Technician, Biotechnologist.
Career development and progression opportunities include:
Career advising and Handshake: Wake Forest's Physics Department identifies Handshake as the primary gateway to WFU-specific career opportunities and resources, supported by the University's Office of Personal & Career Development.
Employment outcomes: Among Wake Physics undergraduates represented in the department's outcomes data, 49% entered the job market; of those graduates, 31% became data analysts and 20% entered research and development.
Graduate and professional study: Among the represented Physics undergraduates who continued their education immediately after graduation, 82% entered graduate programs in physics, engineering, medical physics or biomedical sciences, while another 10% entered medical or dental school.
Salary information: Wake Forest's Physics Department reports a $166,290 median annual salary for U.S. physicists in May 2024; this is an occupation-wide U.S. figure and is not a salary specifically for Biophysics graduates.
Industry exposure: Wake Physics graduates work in engineering, finance, information technology, consulting, data science and machine learning, with employers listed by the department including Google, Lockheed Martin and Microsoft.
Government and research: The department identifies government-funded laboratories and organizations such as the CDC, Department of Defense and NASA among destinations and employers relevant to physics graduates.
Research preparation: Undergraduate students can work with faculty through research groups, URECA summer programs and funded positions, strengthening preparation for graduate research and scientific careers.
Accreditation value: Wake Forest's institutional SACSCOC accreditation covers its baccalaureate degrees, providing recognized institutional accreditation for the degree.
University-wide graduation outcomes: Wake Forest reports that 97% of graduates in recent years were employed or enrolled in graduate programs within six months of graduation.
Further Academic Progression: Graduates can continue into master's or doctoral study in areas such as biophysics, physics, biomedical sciences, medical physics, engineering and related fields. The Biophysics B.S. also supports pre-health pathways, and Wake Forest offers graduate and professional programs that can complement a biophysics background.


US universities use a holistic admissions review. Beyond grades and standardized test scores, they weigh the strength of your overall profile to understand who you are as a student and a person.

Embark on your educational journey with confidence! Our team of admission experts is here to guide you through the process. Book a free session now to receive personalized advice, assistance with applications, and insights into your dream school. Whether you're applying to college, graduate school, or specialized programs, we're here to help you succeed.
